Searchable abstracts of presentations at key conferences in endocrinology

ea0086p193 | Endocrine Cancer and Late Effects | SFEBES2022

Clomiphene Citrate induced changes in the Estrogen and Estrogen receptors in the ovary of female Sprague-Dawley rats

Samson Aina Olawale , Iranloye Bolanle , Ckukwuduben Evangelshane , Rotimi Adebayo

Endocrine therapy in hormone sensitive cancers is on the increase and substances that reduce estrogen level and upregulate estrogen receptor can reduce activities of ovarian cancer. Clomiphene citrate (CC) is a selective estrogen receptor modulator. This study is aimed at investigating how different doses of CC affect estrogen level and level of alpha and beta estrogen receptors in the ovary of adult female rats. Fifty female Sprague-Dawley (SD) rats were divided into 5 groups...